Difficult.

The message "Your profile has not been changed." depends on $current_User->dbupdate()
The plugin however doesn't store the $current_User in the database but stores it's settings in the Plugins section of the database, so the message is correct: $current_User->dbupdate() didn't happen.

Good luck

This solves the problem.

1) Add this function to the class Log in /inc/_core/model/_log.class.php:

	/**
	 * Remove a message from the log
	 * Foppe >> This seems the best way to solve a conflict (two seemingly conflicting messages
	 * when changing User profile through a plugin)
	 * 
	 * @param string the message
	 * @param string the category
	 *  
	 */	
	function remove( $message, $category = NULL )
	{
		if( $category === NULL )
		{ // By default, we use the default category:
			$category = $this->defaultcategory;
		}
		$custom_key = array_keys( $this->messages[ $category ], $message );
		unset( $this->messages[ $category ][ $custom_key[0] ] );
		$this->_count[ $category ] = $this->_count[ $category ] -1;
	}

2) Add the second line after the first in /inc/users/users.ctrl.php on lines 451 *and* around line 531:

			if( $any_plugin_settings_updated )
			{
				$Messages->add( T_('Usersettings of Plugins have been updated.'), 'success' );
				$Messages->remove( T_('Your profile has not been changed.'), 'note' );
			}

The lines with the function remove are the new lines.

As said, this works but I can't see if this is the proper or best way to trigger the problem.

Good luck